Critical Limb Ischemia Definition | Understanding Advanced PAD

Critical Limb Ischemia Definition refers to the most advanced and severe stage of Peripheral Artery Disease (PAD), where blood flow to the limbs becomes critically reduced due to blocked or narrowed arteries. This condition leads to chronic rest pain, non-healing ulcers, or tissue damage in the legs or feet. CLI is a serious vascular disorder that requires urgent medical evaluation, as delayed treatment may increase the risk of infection, gangrene, or possible limb loss.
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