Taza News: Nobel Wins for Immune System's 'Security Guards'
Taza News » reports the 2025 Nobel Prize in Medicine has been awarded to Brunkow, Ramsdell, and Sakaguchi for discovering peripheral immune tolerance. Their breakthrough identified Regulatory T cells (Tregs) and the FOXP3 master switch, revealing how the immune system is prevented from attacking the body. This fundamental science is driving hundreds of clinical trials for autoimmune diseases and cancer. Public interest is surging in companies like Sonoma Biotherapeutics (where laureate Fred Ramsdell advises) and Quell Therapeutics, which are pioneering Treg cell therapies (ABA-101, PTG-007). These treatments aim to harness Tregs to cure conditions like Type 1 Diabetes, Multiple Sclerosis, and enhance new immunotherapies by disarming the Treg shield around cancer tumors. The laureates' work promises a future where serious diseases become "no longer scary, but curable.
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